This paper represents the structural design and dynamic analysis of a 24 storey hotel in Skopje. Applying the latest conceptions for seismic stability and safety of structures, i.e. the plasticity criteria and plastic excursion deformations, the design of the structural system was accomplished. The system itself is a reinforced concrete frame combined with R.C. framed walls. The framed walls are so designed, as to act as seismic energy absorbers. The mathematical model was formulated by electronic computer, while the input data concerning the stiffness characteristics and deformations of the infilled walls are based on experimental results obtained in Japan. The data obtained for the optimal system show that the structure satisfies completely all the requirements imposed by the seismicity criteria of the site of construction.