An extensive experimental testing programme named JETBIS project (Joint Experimental Testing of Base Isolation Systems) was developed within the RELUIS II project (Task 2.3.2) and RELUIS III project (Line 6) involving partners from different Italian universities. This paper describes the seismic tests performed by the research unit of University of Basilicata (UNIBAS) on an isolation system based on Double Concave Friction Pendulum (DCFP) bearings. The DCFP bearing contains two separate concave sliding surfaces and exhibits different hysteretic properties at different stages of displacement response. The main objective of this work is to evaluate the horizontal response of the DCFP isolators by means of controlled-displacement tests and shaking table tests. The experimental model was a 1/3 scaled steel framed structure with one storey and one bay in both directions. Four DCFP bearings with equal properties of the sliding surfaces were considered. In this work, three different sliding surface conditions (with and without lubrication) have been studied. The isolated base model was subjected to 8 natural earthquakes of increasing seismic intensities and considering two mass configurations (with both symmetrical and eccentric masses). The reliability of the design procedure considered for the isolation system was verified also when relevant residual displacements occurred due to previous earthquakes. In this paper, the comparisons between the experimental outcomes and the numerical results of nonlinear time-history analyses using SAP2000 are shown.